Library / Glutathione
Some human studies
Glutathione
Natural antioxidant tripeptide · Longevity · GSH
What it is
A three-amino-acid antioxidant made in every cell, with the highest levels in the liver. It helps neutralise damaging molecules and clear toxins.
What research covers
Taken by mouth, small trials show modest increases in body levels. Evidence for skin lightening and anti-ageing claims is limited and mixed.
Reported side effects
- Generally well tolerated by mouth
- Bloating or cramps
- Rare allergic reactions with injections
Not suitable for, or talk to a doctor first
- Asthma (inhaled forms can trigger wheezing)
- During chemotherapy, without your oncologist's advice
Good to know
- Health regulators in several countries have warned against injecting glutathione for skin lightening.
Legal status
| Australia | Sold as an oral supplement. Injected glutathione is not an approved treatment. |
|---|---|
| United States | Sold as a supplement. Injections are given only in clinical settings. |
| Sport | Not prohibited by WADA at the time of writing. |
Rules change. Check with the TGA (Australia), your local regulator, or WADA for sport.
Key references
- Richie et al. Randomized controlled trial of oral glutathione supplementation on body stores of glutathione. Eur J Nutr, 2015.
General information, not advice. Talk to a qualified healthcare professional before starting, changing or stopping anything.